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Nature 537:185190 Kruegel AC, Gassaway MM, Kapoor A, Vradi A, Majumdar S, Filizola M, Javitch JA, Sames D (2016) Synthetic and receptor signaling explorations of the mitragyna alkaloids: mitragynine as an atypical molecular framework for opioid receptor modulators
doi: 10.1002/jcb.21394

Tetraethyldioxetane and 3,4-dimethyl-3,4-di-n-butyl-1,2-dioxetane
