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ROS also decrease the activity of histone deacetylase (HDAC) which recoil DNA of the histone core to stop transcription, 36,37 and probably increase the activity of Histone acetyltransferase, which uncoils DNA from the histone core to allow transcription
Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial
