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Therefore, erastin treatment alone is insufficient to induce threshold levels of lipid peroxides, implying that DENV depends on ALOX12-dependent lipid peroxidation for efficient replication

Persistent AGERAGE activation can enhance cytokine production and ROS accumulation, creating a microenvironment that favors TGF-1 activation, extracellular matrix deposition, and fibrotic remodeling (145)

In CARE diabetic status compared to nondiabetic status per se was not associated with high concentrations of apoC-III-containing TG-rich lipoprotein particles, if their plasma TG levels were similar [123]
