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Successive structural modifications, principally to confer oral bioavailability and CNS penetration, produced Dihexa: an orally active, BBB-permeant peptidomimetic with no measurable angiotensin receptor activity but extraordinary synaptogenic potency [1,2]

Second, nobody knows the long-term safety profile

Side effects and safety profile Across the combined Phase 3 Tesamorelin database of over 800 treated subjects, the most frequently reported adverse events were injection site reactions (erythema, pruritus, small local hematoma) at roughly 25 percent of subjects, arthralgia and myalgia at 10 to 15 percent, and peripheral edema at 6 to 8 percent

The Certificate of Analysis provides batch-specific analytical data and quality control information relating to the tested material