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Furthermore, comparing Prdx Km for H 2 O 2 with that of GPx and catalase exceeding even the millimolar range [180] suggests that the role of Prdx is rather as a sensor of H 2 O 2 [178] than oxidative stress condition reversal

For example, in the above example E = +0.03 (-0.34) = +0.37 V ) E = E of the electron acceptor E of the electron donor Note: You would see that the E for the reverse reaction gives a negative value E = -0.34 (0.03) = -0.37 V) , i ndicating that the reverse reaction will not be spontaneous under these conditions

The size of CG is directly dependent on the goiters antioxidative environment and its proliferative turnover intensity reflected in DNase I and DNase II activity