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Description
Registered medicines are higher-risk drugs, such as antibiotics or anti-inflammatory medicines, and they must go through a thorough review before they can be sold.

[DOI] [PubMed] [Google Scholar] 86.Gasic K., Korban S.S

Current limitations include the lack of early-phase clinical trials and safety concerns in cirrhotic livers, the lack of specificity and systemic toxicity of available NRF2 inhibitors, the genetic and molecular heterogeneity in HCC tumors, and the absence of validated biomarkers for NRF2 activity and therapeutic response

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