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Common Side Effects While uncommon, some people may experience mild side effects after receiving a B12 injection, including[17]: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling or numbness in the hands and feet These effects are typically short-lived and resolve on their own

Analysis of vitamin levels and deficiencies in bariatric surgery patients: A single-institutional analysis

However, several theories have been proposed such as changes in the blood vessels that supply the peripheral nerves, metabolic and autoimmune disorders with glial cell activation, changes in sodium and calcium channel expression, and central pain mechanisms, such as increased thalamic vascularity and imbalance of the facilitatory/inhibitory descending pathways [2]

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