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Statements in this article are based on available scientific literature and should not be interpreted as evidence of approved medical uses, therapeutic efficacy, or safety in humans
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The gamma-glutamyl cycle should be considered not as a mechanism for amino acid transport but rather a generator of extracellular signals, gamma-glutamyl amino acids, that are converted intracellularly to 5-oxoproline, which activates uptake and/or metabolism of amino acids (74, 75)
