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It is commonly accepted that oxidative stress induced by excess ROS/RNS levels is detrimental to biological functions and is involved in the development of many pathological conditions, such as cardiovascular diseases, neurodegenerative diseases, aging, and cancer (30, 90, 106)

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Nature 444, 444454 10.1038/nature05329 [DOI] [PMC free article] [PubMed] [Google Scholar] Rehnstrom K., Ylisaukko-Oja T., Vanhala R., von Wendt L., Peltonen L., Hovatta I

Migration of B immunoblasts into intestinal, respiratory, and genital tissues
