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In addition, lipid nanoparticles encoding the tumor-associated antigens gp100 and TRP2 mRNA can also induce CD8 + T cell activation thereby shrinking tumors and prolonging the overall survival of treated mice (146)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Lee Y, Warne T, Nehm R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, Garca-Nafra J, Leslie AGW, Shukla AK, et al
J Clin Psychopharmacol 2013;33:719-20
