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The key findings from this clinical program include significant reductions in body weight and fat mass in treatment groups compared to placebo, preferential loss of abdominal and visceral adipose tissue, no changes in serum IGF-1 levels at any dose tested, no negative effects on glucose metabolism or insulin sensitivity, no significant adverse events related to metabolic or endocrine disruption, and safety profile indistinguishable from placebo for most parameters

CMV-specific CD8 + T cells were studied in-depth and evaluated along with SARS-CoV-2specific CD8 + T cells, which served as an internal control virus-specific T cell population

doi: 10.1155/2021/9924314