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Description
Third, we chose to use overall survival as the primary endpoint, which is a hard outcome, providing a comprehensive assessment of the treatment effect in a retrospective study, although the proportion of patients becoming non-self-sufficient and ALSFRS-R total score, used as secondary outcomes, are validated endpoints for trials in ALS
Li, S., Xu, Z
Sorafenib inhibits the phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1, a key negative regulator of translation controlled by mTOR (Sauzay et al., 2018), ( via the mTOR pathway
Accessed 03/07/2024
