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The best plan might still have rules

Theres no clear understanding of why adequate levels of B12 are associated with a reduced risk of obesity, but there are a few theories 9-11 : B12 may influence how the body stores fat B12 is required for proper muscle protein, and low levels could interfere with recovery Insufficient B12 impairs red blood cell production and interferes with oxygen delivery to muscles Key takeaway: There is some evidence linking low B12 levels to a higher risk of obesity in children, adolescents, and adults, but the evidence is too weak to confirm a relationship

Escalation Protocol from Lower Doses Patients starting with 500 mcg can increase to 1000-2000 mcg as needed

43 One RCT evaluated B12 alongside anti-depressants in patients with depression and moderately low B12 status (190300 ng/l) and found that 100% of those on B12, 1000 g per week i.m
