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The high ROS environment lowers the activation threshold of mast cells, causing them to degranulate inappropriately and release a flood of inflammatory cytokines, including histamine, interleukins, and tumor necrosis factor-alpha (TNF-a)

Mol Biol Rep 46(5):53335343 Kaufmann P, Thompson JL, Levy G, Buchsbaum R, Shefner J, Krivickas LS et al (2009) Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III

MOTS-c is a 16-amino-acid peptide encoded inside your mitochondrial DNA
