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Different histamine receptors are found in different parts of the body:[ref] H1 receptors : Found in smooth muscle, endothelial cells (lining the blood vessels), the central nervous system, and mast cells
Marks J, Rice DC , Swisher SG

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Combination of anorganic bovine-derived hydroxyapatite with binding peptide does not enhance bone healing in a critical-size defect in a rabbit model