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Gut integrity declines with age, a phenomenon sometimes called "leaky gut," where the tight junctions between intestinal epithelial cells loosen and allow bacterial products to enter systemic circulation, driving chronic low-grade inflammation

Govt Review] Journal of Physiology and Biochemistry

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250 A recent in vitro study has found that butyrate stimulated adenosine triphosphate release from astrocytes in a cytosolic Ca 2+ -dependent manner, suggesting a potential neuroprotective mechanism worth further exploration