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Antioxidants (Basel) 9, 595

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Furthermore, due to its rigid, fibrous nature, large quantities of chitin can lead to reduced protein absorption or incomplete digestion by interfering with the digestion of proteins and other macromolecules in the stomach 38

GSH is synthesized ( de novo ) from amino acids by the sequential action of g-glutamylcysteine synthetase ( glutamate cysteine ligase ) and glutathione synthetase (Alscher and Hess, 1993) and the de-novo GSH synthesis is required for the elevation of GSH levels as an adaptive response to oxidative stress (Nimse and Pal, 2015)