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Adv Exp Med Biol 521:121 Maes M, Libbrecht I, Van Hunsel F, Lin AH, De Clerck L, Stevens W, Kenis G, de Jongh R, Bosmans E, Neels H (1999) The immune-inflammatory pathophysiology of fibromyalgia: increased serum soluble gp130, the common signal transducer protein of various neurotrophic cytokines

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Then, over time, high cortisol disrupts hormonal balance throughout the body, causing difficult hormonal symptoms like hot flashes