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In Vitro Studies The effect of L-Carnitine on Sertoli cells, which play a crucial role in spermatogenesis and create a suitable environment within the seminiferous tubules, has been investigated by some researchers, demonstrating a direct action of carnitine on the intermediary metabolism in Sertoli Cells, including Palmero et al

( g ) Cells were treated with the IDH1 inhibitor alone and supplemented with propionylcarnitine (Prop-Carn) or butyrylcarnitine (But-Carn) (n = 3 technical replicates representative from 2 independent experiments in each cell line)

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