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Secreted GH can exist in both free and bound states by the GHBP (the secondary domain of the GH receptor) [19]

doi: 10.3390/nu9050477

Science (2021) 373(6550):5660
Further studies indicate that IRP2 binds to p53 and activates the SLC7A11-ALOX12 pathway, thereby inducing ferroptosis (59)