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Vitamin B12 shots are often prescribed for people with: Pernicious anemia (autoimmune destruction of intrinsic factor needed for B12 absorption) Gastrointestinal surgeries (e.g., gastric bypass, ileal resection) Crohns disease or celiac disease Chronic alcoholism Long-term use of acid-reducing medications Vegan diets without supplementation Infants or children with congenital absorption disorders (i.e., vitamin B12 for kids in clinical care) Injections ensure direct delivery into the bloodstream, bypassing the digestive system entirely

Complementary Approaches: The selectivity of AOD-9604 allows flexible combination with other interventions

In the STEP-4 clinical trials, participants who discontinued the medication began to regain weight within a few months

At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times