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Transdermal forms of vitamin B 12 are available over the counter, but this route of administration has not been validated clinically in the setting of vitamin B 12 deficiency and should not be relied upon for treatment

Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients

The combination of products that make up the Lipo-B (MIC) injection are methionine, inositol, choline, and cyanocobalamin (vitamin B12)

These symptoms are usually temporary and can often be managed by taking the supplement with meals or adjusting the dose