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Crohns disease and ulcerative colitis, the two main forms of IBD, are widespread conditions (Khor et al., 2011)

doi: 10.1002/jmri.21966

The oxidation of this residue yields a sulfenic acid derivative, this inactivating the peroxidase activity of Prx6 towards H 2 O 2 and hydroperoxides of phospholipids

Our coimmunoprecipitation study showed that LPS enhanced CRM1/HMGB1 complex formation (Figure 7D), whereas, overexpression of GSTP substantially attenuated interaction between HMGB1 and CRM1