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The Broad Institute, a genomic research center run by MIT and Harvard, maintains a database called the Connectivity Map that tracks how compounds shift gene expression across thousands of human cell lines

To mitigate disease progression, tailored therapies aimed at eliminating pathogenic plasma or B-cell clones are needed for monoclonal gammopathy-related glomerulonephritis [37, 38]

The right dose for a 30-year-old athlete with an acute Achilles strain is different from the right dose for a 55-year-old patient in post-surgical recovery

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