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McLean JB, Moylan JS, Andrade FH

Compartment specific mitochondrial dysfunction in Drosophila knock-in model of ALS reversed by altered gene expression of OXPHOS subunits and pro-fission factor Drp1

ALADIN III Study Group

The process works through several key steps: Folate converts to 5-methyltetrahydrofolate (5-methylTHF), which circulates in blood This form donates methyl groups necessary for DNA methylation After transferring methyl groups, SAM becomes S-adenosylhomocysteine (SAH) Much of American men over age 60 take dietary supplements containing folic acid [20]
