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However, most obese humans have elevated plasma leptin levels, implying they may have leptin resistance rather than leptin deficiency

Weng TY, Tsai SYA, Su TP

The GHSR-1b receptor exhibits widespread tissue distribution and exhibits an ability to co-localize with the GHSR-1a receptor causing a subsequent attenuation of activity through an increased internalization of the active receptor

Liang, M
