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Because this formula contains niacinamide, a few people might experience a flushing reaction (warmth, redness of the skin) or slight itching, although niacinamide usually does not cause the intense skin flush that niacin (nicotinic acid) does

The NNMT enzyme it inhibits is constitutively expressed in adipose tissue and liver, meaning timing relative to meals is less critical than consistency

Ageing hallmarks exhibit organ-specific temporal signatures
