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Collectively, these findings suggest that neuronal HDAC9 overexpression mitigates A pathology across multiple brain regions in 5xFAD mice

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Administration of dexamethasone (a synthetic glucocorticoid lacking MR activity) [64,65] or corticosterone (primary glucocorticoid in rodents) [66] reverses this phenotype

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The 2017 classification regrouped the EDS into six groups (A to F) according to underlying genetic and pathogenic mechanisms [1]

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