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[DOI] [PubMed] [Google Scholar] Gesty-Palmer D, Chen M, Reiter E, Ahn S, Nelson CD, Wang S, Eckhardt AE, Cowan CL, Spurney RF, Luttrell LM, et al
While human mutations leading to isolated GH deficiency have been found in the GHRHR gene, to date no such mutations have been identified in the gene encoding the ligand, GHRH
Furthermore, ML210 takes the form of diacylfuroxans, which transform into its corresponding -nitroketoxime, JKE-1674, within cells
It is carcinogenic, particularly in the cells of the GI tract and liver
