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Monitoring: Regular colonoscopies, blood tests, and imaging are important for monitoring disease activity, medication safety, and cancer surveillance (long-standing Crohns colitis increases colorectal cancer risk)

Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted

Studies have also reported stimulation of proteoglycan and collagen synthesis in chondrocyte preparations, pointing to a meaningful role in joint research independent of its metabolic activity