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Description
In contrast, chronic ischemic heart disease involves prolonged, low-grade oxidative stress contributing to maladaptive remodeling and fibrosis (Loffredo and Carnevale, 2024), with ROS sources potentially more linked to chronic inflammation and metabolic alterations, suggesting different therapeutic targets than acute scavenging
SHMT is likewise upregulated in multiple cancers and serves as a predictor of unfavorable clinical outcomes 130,131,132,133
10.1007/s00438-016-1177-0 Mol
Bai T, Wang S, Zhao Y, Zhu R, Wang W, Sun Y
