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Additional Information and Declarations Competing Interests Norhayati Mohd Noor is an Academic Editor for PeerJ

Secondary MR A prospective, multicentre study in 103 patients with either primary or secondary MR showed substantial discordance in the severity of MR as assessed with either CMR or echocardiography on the basis of either the American Society of Echocardiography integrated method or the proximal isovelocity surface area (PISA)-based regurgitant volume 19

A Common Haplotype in the Complement Regulatory Gene Factor H ( HF1/CFH ) Predisposes Individuals to Age-Related Macular Degeneration

reported machine-learning models for predicting the occurrence of respiratory diseases using climatic and air-pollution factors (47)