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Fewer systemic side-effects compared to hGH Because AOD 9604 does not significantly elevate IGF-1 or impair glucose/insulin regulation (in trials), it may carry lower risk of some growth hormone-associated adverse effects

Deficiency in vitamin B6 is commonly linked to malnutrition, alcoholism, malabsorption syndromes, or as an adverse effect of certain medications, such as cyclosporine, hydralazine, cycloserine, penicillamine, isoniazid, levodopa, phenelzine and chemotherapy treatments (, , , )

In clinical trials, AOD9604 was shown to reduce abdominal fat mass in overweight individuals without affecting lean mass or glucose levels. Ng et al., Obesity Research & Clinical Practice 2

The relatively short half-life (24 hours) supports twice-daily dosing for more consistent effects, though once-daily protocols are more common and convenient