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gxl glutathione accelerator Metabolic orchestration driven by GGCT: diverting glutamine to biosynthesis while enhancing glucose anaplerosis for tumor proliferation Glutathione-activated DNA-Au nanomachine as targeted

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This modification reduces the susceptibility of phospholipids to oxidative damage, thereby enhancing cellular resistance to ferroptosis

gxl glutathione accelerator Metabolic orchestration driven by GGCT: diverting glutamine to biosynthesis while enhancing glucose anaplerosis for tumor proliferation Glutathione-activated DNA-Au nanomachine as targeted

MaatoukLCompagnionACSauvageMCBemelmansAPLeclere-TurbantSCirotteauVet al

gxl glutathione accelerator Metabolic orchestration driven by GGCT: diverting glutamine to biosynthesis while enhancing glucose anaplerosis for tumor proliferation Glutathione-activated DNA-Au nanomachine as targeted

Heldin, C

gxl glutathione accelerator Metabolic orchestration driven by GGCT: diverting glutamine to biosynthesis while enhancing glucose anaplerosis for tumor proliferation Glutathione-activated DNA-Au nanomachine as targeted

Construction regulation networks and prediction drugs After searching the miRNAs targeting biomarkers from the miRDB and miRWalk database, a total of 36 intersecting miRNAs were predicted, with 7, 18, 5, and 6 miRNAs were predicted to target APEX1, ECHDC2, NME3, and PUS1, respectively

gxl glutathione accelerator Metabolic orchestration driven by GGCT: diverting glutamine to biosynthesis while enhancing glucose anaplerosis for tumor proliferation Glutathione-activated DNA-Au nanomachine as targeted

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