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Inhibition of STAT3 phosphorylation by colchicine regulates NLRP3 activation to alleviate sepsis-induced acute lung injury

49,72 Dysregulation of this feedback contributes to chronic inflammation, fibrosis, and tumorigenesis, and restoring this balance represents a promising therapeutic strategy

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3 In the LLNA, FITC was found to be an extreme sensitizer with an EC3-value of 0.14% (3.6 mM), and 15.5% of the lysine peptide was depleted after 24 h in DPRA when a 10-fold excess of FITC was used