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B 12 deficiency can also result in neurological problems

Diet, gut health, medications, and even genetics influence how efficiently histamine is processed

Before taking, speak with your doctor if you are allergic to vitamin b12, have a genetic condition called optic atrophy, have blood in your urine, polycythemia, an ongoing infection, low iron or folate levels, are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed

The above procedure was repeated with inhibitor concentrations spanning 0.3 60 M to determine the effective concentration (EC 50 ) required to inhibit 50% NNMT activity in cultured adipocytes