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The authors detected B[ a ]P at a very high mean concentration of 163.87 68.53 ng/m 3 , noting that mean PAHs levels were higher in classrooms in urban schools as compared to suburban and residential schools

However, lethal autophagy in cells under physiological or pathological conditions is rarely triggered, and it is not practical to treat diseases by inhibiting lethal autophagy in clinical applications

CLINICAL CASE (continued) Various treatment options are reviewed with the patient, including EPO and 3 recently approved drug therapies for SCD: voxelotor (a modifier of hemoglobin oxygen affinity), L-glutamine (an antioxidant), and crizanlizumab (a P-selectin inhibitor)