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Moller J, Jorgensen JO, Lauersen T, et al
1 A few key points for clinicians: Short half-life (1012 min): This quick clearance supports physiologic GH pulses rather than continuous stimulation. Preserved feedback loops: IGF-1 and somatostatin feedback acts to keep GH levels within physiologic norms
5 Smurf1 is upregulated via KRAS/AP-1 axis
[DOI] [PubMed] [Google Scholar] 407.Zegota H
