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Research demonstrates that GHK-Cu influences gene expression patterns to favor tissue repair over inflammatory damage, downregulating pro-inflammatory cytokines while upregulating protective factors including antioxidant enzymes and tissue repair mediators

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Furthermore, mechanical ventilation is a risk factor for cerebral inflammation and brain injury due both to the pulmonary inflammatory cascade, which migrates systemically to the brain, and to hemodynamic instability for the reduction in cardiac output and high pulmonary resistance caused by the distension of alveoli and compression of pulmonary capillaries 132

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