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Description
Established Safety Profile Across all clinical studies, AOD-9604 demonstrated excellent safety and tolerability

not approved for human or veterinary application.

The deletion of PNPLA2 in adipocytes resulted in reduced PPAR activity and expression of target genes, including lower UCP1 protein levels and when exposed to cold, mice were cold sensitive (140)

Unfortunately, no exact reference range for these markers has been determined so far [56,64,65,66,67,68]
