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doi: 10.1016/S1474-4422(12)70238-7
10.3892/ijo.30.4.905 220 SharmaR
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We hypothesize that irisin reduces lactate synthesis by inhibiting the HIF-1/LDHA pathway via SIRT1-mediated deacetylation and repairs mitochondrial function through the PGC-1/UCP2 pathway, ultimately improving neuronal damage
