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The results suggest that NZB/W mice have increased expression of senescence markers such as FOXO4, rH2AX, and p16, and that senescent cells can be targeted in the kidney of patients with lupus
Conclusions The diagnostic and therapeutic potential of targeting cholesterol metabolism for cancer has recently gained considerable attention

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Thus, even in the absence of GHSR1as natural ligand, GHSR1a appears to have significant physiological effects via these proteinprotein complexes
