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Description
doi: 10.1530/EJE-14-0011 23

PASI scores, photographic documentation, and symptom tracking provide objective measures of progress

3 The risk factors for methotrexate AEs include higher doses (3.5 g/m 2 ), rapid infusions, preexisting kidney impairment, older age (aged 50 years), and the concurrent use of medications that are nephrotoxic or that impair methotrexate clearance (eg, proton pump inhibitors, aminoglycosides, nonsteroidal anti-inflammatory drugs, penicillin and penicillin derivatives, amphotericin, probenecid)

CYP3A4, cytochrome P450 3A4
