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Gurney H, 2024, Data from A phase Ib, open-label study evaluating the safety and efficacy of ipatasertib plus rucaparib in patients with metastatic castration-resistant prostate cancer, Other | 2024 Pook D

The risk is much higher in men and women with gonadal dysgenesis, specially forms that arise from early gonadal differentiation defects, such as mutations in SRY and WT1, than in individuals with ovotesticular DSD or with hormone synthesis or action disorders (for example, androgen insensitivity) [168,169,170]

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Just because some drugs are marketed as for research use only, Health Canada says that does not make them legal or exempt from regulatory requirements