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However, they can last longer depending on several factors: Bacterial burden Type and dose of antimicrobial used Efficiency of detox pathways (liver, lymph, gut) Pre-existing inflammation or comorbidities Timeline Overview Mild cases : 24 days Moderate cases : 57 days Severe cases : 1014 days (less common) If symptoms persist beyond one week, a review of your protocol with a practitioner is strongly advised

All these models are also helpful to test potential therapeutic strategies for LS, such as gene augmentation therapy or bezafibrate treatment, which promote mitochondrial biogenesis and support neuronal morphogenesis (Lyu et al., 2022)

10.1385/ct:3:3:219 15 CaoJ

doi: 10.1034/j.1601-183x.2003.00037.x 73 Ruiz-LarreaM