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The Phase 2 clinical trial showed roughly 2-3 kg more fat loss than placebo over 12 weeks, with no impact on blood sugar, insulin, IGF-1, or any hormonal marker

It became really, really itchy around days 9-10

The observed decrease in serum ferritin concentration might have been secondary to depletion of the bodys iron reserves after bariatric surgery as the prevalence of anemia in the Optimum 2.0 group increased from 13% at T24 to 18% at T36, suggesting that the bodys iron stores were not sufficient to prevent patients from developing iron-deficiency anemia

Most data are extrapolated from NNMT biology and animal work