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After removing the bone flap, CCI was performed with a controlled impactor device at a speed of 4 m/s, a depth of 1 mm and a 150-ms impact duration (Impact One TM Stereotaxic Impactor, Leica, Milan, Italy)

Imaging techniques have challenged previous ideas about the peripheral origin of FM and have provided evidence for altered central nervous system nociceptive/pain processing and morphology in fibromyalgia

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