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Description
Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe
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Researchers attribute ES2s effectiveness to its ability to bind to FOXO4, thereby disrupting the interaction between FOXO4 and p53 [128]
The PROTAC Optimization Kit for PARP1-Cereblon Binding comes in a convenient AlphaLISA format, with enough PARP1 Degrader iRucaparib-AP6 PROTAC, assay buffer, recombinant purified PARP1 and CRBN (Cereblon)/ DDB1(damage specific DNA binding protein 1)/Cul4A (cullin 4A)/ Rbx1 (ring-box 1) complex for 384 reactions
