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Maybe this fact contributes to the non-significant decrease of tHcy in group S

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Closely linked to spatial organization is the tumor microenvironment (TME), which plays an essential and active role in shaping melanoma cell responses to therapy and in stabilizing drug-tolerant persister states
Singer E, Judkins J, Salomonis N, Matlaf L, Soteropoulos P, McAllister S, Soroceanu L
