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For something to be added to the WADA Prohibited List, it must meet two of the three inclusion criteria: 1) it has the potential to enhance performance 2) it poses a health risk to athletes and 3) it violates the spirit of sport
IGF1R autophosphorylation also recruits Shc, which leads to Grb2/SOS/Ras activation and downstream ERK1/2 phosphorylation
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